Cross post reply back from Dose-Net, Re: ICRP 68

[mozley@darius.pet.upenn.edu (P. David Mozley)]

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>Resent-Date: Mon, 9 Sep 1996 08:05:21 -0400 (EDT)
>Date: Mon, 09 Sep 1996 07:42 -0500 (EST)
>From: STABINM@ORAU.GOV
>Subject: Cross post to Dose-Net, Re: ICRP 68 -Reply
>To: radsafe@romulus.ehs.uiuc.edu
>Cc: DOSE-NET@ORAU.GOV
>Errors-To: DOSE-NET-ERROR@CSLAB1.ORAU.GOV
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>>So no one has any opinion on whether the dose modeling in ICRP 68 is
>any good or not?  I asked the question and got no responses at all.

>I'm not sure what the exact question was, but here is a quick overview
>of my take (although I will admit that I have not spent great amounts of
>time working with this document yet).
>
>Occupational stuff:
>
>Revised lung model - generally seems to be receiving acceptance as an
>improvement over the ICRP 30 model, albeit much harder to use.  But the
>technical basis seems quite sound to me.
>
>Revised biokinetic models - physiologicall based - definitely an
>improvement in concept over the ICRP 30 nonrecycling models.  I have
>not yet seen demonstrations of the performance of these models with
>"real world" data.
>
>Excretion models for systemic activity - badly needed addition.  In the
>ICRP 30 models, systemic activity seems to have just "evaporated" into
>the ether or something.  The dose to the urinary bladder is often very
>significant.
>
>Nuclear Medicine stuff -
>
>The dose estimates appear to be based mostly on the ICRP 53 (1988)
>data, some of which are out of date now.  Particularly, the dosimetry for
>Tl-201 for the testes is no longer valid.  This is probably the most
>significant change, but other kinetic models have been updated as well.
>We have a NUREG (6345, publ 1996) that has up-to-date
>radiopharmaceutical dosimetry for adults for many compounds.  We hope
>to issue updates periodically, and extend it to pediatrics, if the NRC is
>interested.  BTW, there was an interesting study at our symposium this
>May from Smith et al. of the UK on Tc-99m DMSA dosimetry in children,
>which pretty well characterizes the age-dependence of the dosimetry
>for the compound, IMO.  But dosimetry compendia for
>radiopharmaceuticals go out of date relatively quickly, and should be
>used with caution.
>
>Mike Stabin
>Radiation Internal Dose
>  Information Center
>Oak Ridge, TN
>
>