Re: Tritium and plastic

[JMUCKERHEIDE@delphi.com]

Right, but 450 is an instantaneous LET dose. Somebody must have given animals
a high H-3 dose? (Is a "dose-rate" factor of 2 justified?) 

Regards, Jim

> JMUCKERHEIDE@delphi.com wrote:
>  
> > Al, Wes, all,
> 
> > Based on?  what is the animal data?
>  
> > Regards, Jim Muckerheide
> > jmuckerheide@delphi.com
> 
> > > Wesley M. Dunn wrote:
> 
> > > > Well, taking the LD 50/30 as approximately 450 rem (Whole Body Acute
> > > > Dose -- probably reasonable with THO with an effective 1/2 life of
> > > > about 10 days):
> 
> > > > ALI (Oral; THO) = 80 mCi = 5 rem
> 
> > > > LD 50/30 ~7 Ci (single intake)
> > > I have used 8 Ci (single intake) as a lethal dose (e.g. LD 50/30).  So we es
> sentially agree.  Al Tschaeche  xat@inel.gov
> 
> There are no data that I know of.  The 8 curies is only based on a
> calculation that says:  if you have a one time intake of 8 curies of
> tritium as tritiated water, you will receive a committed effective dose
> equivalent of 450 rem.  The 450 rem is just one of a bunch of numbers
> that run from 300 to 600 rem that various people have used as the lethal
> dose in 30 days to 50% of the population receiving that dose.  Al
> xat@inel.gov