Re: Russian Exposure Data - A Goldmine?

["Otto G. Raabe" <ograabe@ucdavis.edu>]

February 9, 1998
Mobile, AL

Greeting from the HPS midyear meeting being held this week in Mobile.

The indication from the Russian data that there is a cancer risk threshold
for lung cancer at about 4 kBq intake agrees with the predictions that I
have made and published based on the beagle studies at Battelle Pacific
Northwest Laboratories and at the Lovelace Inhalation Toxicology Research
Institute that there is an effective threshold at a life-time lung dose of
about 1 Gy (2000 rem !). See, for example,

1988 Raabe, O.G. Respiratory System Risk Estimation for Inhaled
Radionuclides Utilizing Lognormal Response Surfaces. Annals of Occupational
Hygiene 32, Supplement 1: 1129-1139.

1989 Raabe, O.G. Extrapolation and scaling of animal data to humans:
Scaling of fatal cancer risks from laboratory animals to man. Health
Physics 57 (suppl.1): 419-432.

1994 Raabe, O.G., Three-Dimensional Models of Risk from Internally
Deposited Radionuclides, Chapter 30, pp. 663-656 in Internal Radiation
Dosimetry (O.G. Raabe, Ed.), Medical Physics Publishing, Madison, WI. 

1996 Raabe, O.G., O Wunder! The inverse dose-rate effect is quelled by the
effective threshold, IRPA 9, 1996 International Congress on Radiation
Protection, International Radiation Protection Association, Proceedings
2:378-380.

		*****************************************************
		Prof. Otto G. Raabe, Ph.D., CHP
                [President, Health Physics Society, 1997-1998]
		Institute of Toxicology & Environmental Health (ITEH)
		     (Street address: Old Davis Road)
		University of California, Davis, CA 95616
		Phone: 530-752-7754  FAX: 530-758-6140 [NEW AREA CODE]
		E-mail ograabe@ucdavis.edu