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Re: Re[2]: EDE from FDG



For a bone scan, in which the standard dose is 20 mCi (740 MBq), the 
radiation absorbed dose in rad has been estimated as follows to a 
standard adult person (ref:Practical Nuclear Medicine; Palmer, Scott 
and Strauss, W.B. Saunders & Co, 1992):

total body 	0.13

red marrow 	0.56

bladder wall	2.6  ( 2 hour void)
		6.2  ( 4.8 hour void)

ovaries		0.24 ( 2 hour void)
	        0.34 ( 4.8 hour void)

testes		0.16 ( 2 hour void)
                0.22 ( 4.8 hour void)		


		Mike Quastel
		Inst. of Nuclear Medicine
		Soroka Medical Center
		POB 151, Beer Sheva, Israel 84101
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On Wed, 13 May 1998, Ruth Weiner wrote:

> 
>      I recently had a bone scan and was injected with Tc-99.  Using my 
>      handy Pink Book (now a Blue Book) I calculated the EDE to be about 60 
>      mrem.
>      
>      Clearly only my own opinion.
>      
>      Ruth Weiner
>      rfweine@sandia.gov
> 
> 
> ______________________________ Reply Separator _________________________________
> Subject: Re: EDE from FDG
> Author:  alstonc@odrge.odr.georgetown.edu at hubsmtp
> Date:    5/13/98 6:41 AM
> 
> 
> Scott
>      
> It's not, however, considerably greater than the EDE from other nuc med 
> diagnostics, but, in fact, readily comparable. Somehow, it seems intuitively 
> "right" that it takes a bigger dose to get physiological data, than to get 
> anatomical data, doesn't it?
>      
> chris alston
>      
> At 10:41  05/12/98 -1000, you wrote:
> >I was recently asked to compare the dose received from a PET exam to a 
> >chest x-ray.  The best reference I found was in the Journal fo Nuclear 
> >Medicine 1991; 32:699-706.   In Table 6, the EDE for an intravenous 
> >injection of FDG is stated as 2.4E-2 mGy/MBq.
> >
> >That would be 0.09 rad/mCi in nostalgic units.  Considering a typical PET 
> >study may require 10 mCi of FDG, that means the EDE would be 0.9 rad,
> >or 900 mrem.
> >
> >I was very surprised by the magnitude of this value.  Table 3.27 of NCRP 
> >100 states the EDE of a chest exam to be 0.08 mSv, or 8 mrem.  The EDE 
> >from a CT exam is stated as 1.11 mSv, or 111 mrem.    The EDE from a 
> >barium enema exam is 4.06 mSv, 0r 406 mrem.
> >
> >As you can see, the EDE from a FDG PET exam is considerably greater 
> >than other diagnostic exams.  This was news to me, so I thought it might 
> >be interesting to share with you.
> >
> >                    *****
> >Frequently Asked Questions (FAQ) for Medphys at: 
> >http://www.mindspring.com/~sherouse/MPFAQ.html
> >
> >
> >
>