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RE: Radioiodine in cows
Lorna,
This may sound basic; but make sure you know the chemical form of the
Iodine. If it is NaI the paper quoted by Joe will be helpful; however if
it is tagged to a hormone being injected into the cow then the reference
quoted may not be sufficient. The study reference is quite interesting.
You might enjoy reading it anyway.
JERRY THOMAS
At 02:38 PM 09-06-98 -0500, you wrote:
>You can get an idea from Lengemann, Radioidine in the milk of cows and
>goats after oral administration of radiodate and radioiodide, Health
>Physics, vol 17, pp 656-569, 1969.
>
>Joe Alvarez
>Auxier & Associates, Inc.
>10317 Technology Dr., Suite 1
>Knoxville, TN 37932
>jalvarez@auxier.com
>Tel: 423-675-3669
>FAX: 423-675-3677
>
>-----Original Message-----
>From: Lorna Bullerwell [SMTP:ljb1@cornell.edu]
>Sent: Tuesday, June 09, 1998 11:33 AM
>To: Multiple recipients of list
>Subject: Radioiodine in cows
>
>Hi all,
>
>We have a researcher here who wants to inject 10 mCi of I-125 into a cow.
>He is telling us that almost all of the iodine will be excreted out of the
>cow via milk, urine and feces within a 36 hour period. He is basing this
>on the iodine being bound to bovine Luteinzing Hormone and studies of the
>hormone in rats. This has brought about a few questions that I hope
>someone out there in RADSAFEland may have some insight into.
>
>I was Skrable-ized at Lowell, so I am fully aware of retention functions,
>etc. I also know that based on compound, there are different classes for
>inhalation, depending on how long material stays in the lung. I don't
>recall any discussion about different forms of isotopes behaving
>differently in the body based on certain compounds being injected into an
>animal, human or otherwise. I couldn't find any discussion of this type of
>thing in any of my reference books, which are all based on human exposures
>anyway. Does anyone know how differently radioiodine behaves in cows vs
>people? Is anyone aware of any references for stay times for different
>compounds? Do pretty much all compounds end up with the same behavior in
>regards to radioactivity in the body? Our main problem at the moment is
>trying to determine ahead of time how long the cow needs to remain in an
>isolated stall before it can rejoin the herd and release all excreta
>directly to the environment. While in the stall, we can deal with any
>wastes generated, so that isn't really the issue. Based on what I have
>looked up in the human data, a significant amount of iodine should still be
>in the cow after 36 hours, especially when you are talking about
>environmental levels. Can anyone offer any insight?
>
>Please respond directly to me, unless you feel others may be interested in
>this topic. Thanks in advance. Liz, any ideas?
>
>Lorna
>***********************************************************************
>Any statement above is 100% my responsibility.
>Don't blame Cornell!
>***********************************************************************
>Lorna Bullerwell Phone: (607) 255-8816
>Radiological Safety Specialist Fax: (607) 255-8267
>Cornell University mailto:ljb1@cornell.edu
>Department of Environmental Health and Safety
>Laboratory and Radiation Safety Section
>125 Humphreys Service Building, Ithaca, NY 14853
>************************************************************************
>