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Re: KI Question
In Poland, liquid KI was administered to neonates at a dose of approximately 15mg . Children under five were administered a dose of about 50 mg and children over 5 received a dose of about 70 mg. In Poland, no readily detectable long term disturbance in thyroid function was found as a result of a single dose of KI in children. ((See Iodide Prophylaxis in Poland After the Chernobyl reactor Accident:Benefits and Risks, by Nauman ANd Wolff, Am Journal of Medicine, Vol 94, May 1993)
>>> Mike Lantz <mlantz33@cybertrails.com> 04/28 10:08 PM >>>
Could Patricia or anyone comment on these related questions:
For neonates in Poland, I believe that the KI was administered in liquid form in maternity hospitals by medical personnel. In the US, if a need were perceived for KI, 130 mg pills would be planned to be broken into much smaller estimated portions (16 or 32 mg?) and given to neonates by parents in a rushed situation. Aren't there documented concerns related to KI overdosing of neonates? Does anyone else see a difference in the Poland data and a possible experience in the US?
Patricia Milligan:
KI was administered on day 4 of the accident, which was very late, although it is estimated that approximately a 40 to 45% reduction in thyroid burden was achieved by thyroid blocking and milk restrictions in the 11 provinces treated. (See "The implementation of Short-term countermeasures After a Nuclear Accident, Proceeding of an NEA Workshop Stockholm", Sweden, 1-3 June 1994, OECD 1995). But because of the low iodine concentrations in Poland, it is doubtful that any epidemiological studies could detect excess cancers resulting from the intake of radioiodine. I think the most useful information from the Polish experience is the widespread use of KI across a population with relatively few side effects and no fatalities.
Kevin Goldsmith:
Does anyone know if there has ever been a study done to determine the
possibility of more deaths resulting from allergic reactions to KI than
from thyroid cancer after an accident.
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