Re: Down Syndrome and Radiation Exposure

["Björn" Cedervall <bjorn_cedervall@hotmail.com>]

Regarding the cause of Down's syndrome: There is a topic of genomic
instability that have come up over the last 6-7 years approx. - and
which be of high relevance to non-disjunction phenomena as well as
that of the non-threshold (one hit) discussion. Genomic instability can
probably be due to several different underlying malfunctions. One of
these may be imperfections of the mitotic spindle. Comments?
Refs for Medline: Search for names like Holmberg, Meijer, Johansson,
and Lambert (I think prof. Bo Lambert will give a talk about some of this
at the upcoming ICRR conference in Dublin).

bjorn_cedervall@hotmail.com
In San Francisco this and four more days - then back to Stockholm.


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