RE: Cancer treatment question

["Harmon, Terry O'Devah (ONF) " <onf@bechteljacobs.org>]

Chapter 9 of Introduction to Radiobiology by Maurice Tubiana, Jean Dutreix,
and Andre Wambersie is devoted to the effects of hyperthermia on radiation
damage.  Hyperthermia  causes increased cell death by itself.  This is
further increased by irradiation.  The thermal enhancement ratio (TER) is
the ratio of  the doses producing the same effect at physiological
temperature (Dph) and at the hyperthermic temperature (Dth).

TER depends on the temperature, the period of heating and the time interval
between heat and irradiation.  The effect is greatest when heat and
irradiation are applied simultaneously.

Terry Harmon
Sr. Health Physics Tech
Kelly Scientific Resources
Email: harmonto@ornl.gov

	-----Original Message-----
	From:	Scott D Kniffin [SMTP:Scott.D.Kniffin.1@gsfc.nasa.gov]
	Sent:	Wednesday, July 28, 1999 5:12 PM
	To:	Multiple recipients of list
	Subject:	Cancer treatment question

	Hi all, one for the Med people here,

	One of my co-workers is going to be getting radiation therapy as a
follow
	up to cancer surgery and the radiation is to be followed by about 30
min of
	heat therapy.  I've covered the radiation aspects with this person,
but the
	heat follow up is a bit of a mystery.  The doctor said something
about it
	helping the radiation work better.  Can anyone give me a more
satisfactory
	answer to pass along, please?  

	My gratitude and thanks, as always, 

	Scott Kniffin
	RSO Unisys Federal Systems, Lanham, MD
	CHO Radiation Effects Facility, GSFC, NASA
	mailto:Scott.D.Kniffin.1@gsfc.nasa.gov

	The opinions expressed here are my own. They do not necessarily
represent
	the views of Unisys or NASA.  This material has not been reviewed by
my
	manager or NASA.  
	
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