[ RadSafe ] carcinogenicity of uranium

[Franz Schönhofer]

Yes, I have not only problems, but what you provide is what has been
rejected already several times at RADSAFE. 

Citing a "R. Fairley" is simply nonsense, when you refer (also in your link)
to Ian Fairley, who is a very well known agitator for Greenpeace. He has
worked for Greenpeace and this more than dubious "European somewhat" that
consists of a tiny group of (the very few) green members of the European
parliament and has nothing to do with either the European community or the
European parliament. This is a blatant misuse of the "label" "EU community"
and "European parliament".  Concerning his nonsense he contributed about
tritium there is only acceptable for a good laugh. 

Your second citation I cannot judge, because I am not an expert in this
field. 

Nevertheless I want to tell all RADSAFErs, that I do not support what you
write. Your messages are in my opinion not worse than many others. So I do
not recommend that you should be banned from the list. I just recommend that
you either voluntarily leave the list because of your obvious
non-professionality or that RADSAFErs should ignore your messages. (Reading
"Ian Fairley" was to much a temptation to answer.)

Another topic is of course your interference by writing to employers. This
is more than distainful, in my country this would be a clear case of a
lawsuite, which you would loose without any doubt and and you would have to
pay enourmous sums as compensation. Accept (or not) my deepest disdain.

Below you find my address,you find my status (being retired), my private
e-mail address is in the messenger line. Why do you not give us your
coordinates? (I asked that already once.) Why do you use alias? Probably
because you are one of these half educated, failed students, who need some
engagement, which can be easily found in the green and anti-nuclear field?

 
Franz Schoenhofer, PhD
MinRat i.R.
Habicherg. 31/7
A-1160 Wien/Vienna
AUSTRIA


-----Ursprüngliche Nachricht-----
Von: radsafe-bounces at health.phys.iit.edu
[mailto:radsafe-bounces at health.phys.iit.edu] Im Auftrag von James Salsman
Gesendet: Mittwoch, 14. April 2010 03:57
An: radsafe at health.phys.iit.edu
Betreff: [ RadSafe ] carcinogenicity of uranium

Instead of further discussion about me, I'm hoping we can discuss the
primary underlying issue, which seems to be:  Is inhaled uranium
carcinogenic?  There are peer reviewed papers on both sides of this
issue.  Recently, they have been tending towards the affirmative,
especially in literature reviews which seem to have been unanimous on
the question since 2004. I did a PubMed search to find the most recent
literature review and individual empirical study (because Jeff Terry
told me he prefers them to reviews) and below is what I found. I'm
hoping we can discuss these sources on their merits without discussion
of personalities.

Fairlie, R. (2009) "Depleted uranium: properties, military use and
health risks" Medicine, Conflict and Survival, vol. 25, no. 1, pp.
41-64, Review, http://www.informaworld.com/smpp/content~content=a908923788
-- abstract: "... Particular attention is paid to the evidence of DU's
health effects from cell and animal experiments and from epidemiology
studies. It is concluded that a precautionary approach should be
adopted to DU and that there should be a moratorium on its use by
military forces. International efforts to this end are described." The
body of the article discusses carcinogenicity studies in detail.

LaCerte, C., et al. (2010) "Particulate depleted uranium is cytotoxic
and clastogenic to human lung epithelial cells" Mutation
Research/Genetic Toxicology and Environmental Mutagenesis, vol. 697,
no. 1-2, pp. 33-37, http://dx.doi.org/10.1016/j.mrgentox.2010.01.013
-- abstract: "... DU is suspected to be a carcinogen, potentially
affecting the bronchial cells of the lung. Few studies have considered
DU in human bronchial cells. Accordingly, we determined the
cytotoxicity and clastogenicity of particulate DU in human bronchial
epithelial cells (BEP2D cells). DU induced concentration-dependent
cytotoxicity in human bronchial epithelial cells, and was not
clastogenic after 24 h but induced chromosomal aberrations after 48 h.
These data indicate that if DU is a human bronchial carcinogen, it is
likely acting through a mechanism that involves DNA breaks after
longer exposures."

Any problems with those studies?

Sincerely,
James Salsman
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