[ RadSafe ] Cl-36 in Nuclear Medicine?

Vernig, Peter G. Peter.Vernig at va.gov
Fri Jul 16 11:47:45 CDT 2010


Gary,

I was not aware of the 0.01% but IMO that might as well be 0.  You'd have to give such a high dose to take advantage and then you have all those regular betas.  I just can't see it.

 Any opinions in this e-mail are solely those of the author, and are not represented as those of the VA Eastern Colorado HCS, the Dept. of Veterans Affairs, or the US Government.

Peter G. Vernig,RSO


-----Original Message-----
From: radsafe-bounces at health.phys.iit.edu [mailto:radsafe-bounces at health.phys.iit.edu] On Behalf Of Cary Renquist
Sent: Friday, July 16, 2010 10:43 AM
To: radsafe at health.phys.iit.edu
Subject: Re: [ RadSafe ] Cl-36 in Nuclear Medicine?


0.01% of the EC involves a B+...
Being a relatively low energy B+ (ave 50 keV max 120 keV), one can get fine resolution of the origin of the B+ (the B+ won't travel very far before annihilating). 
My guess is that it could be used for some of the small animal PET scanners as a marker source.  Another possibility would be as a test of an imaging systems resolution.
Imaging technology is getting to the point where the limits on resolution are due to the "fuzziness" of the source and not on the detection technology.  An imaging system might have an intrinsic resolution of 1 mm, but if the B+ travels 2 mm before annihilation then your resolution is limited by that...

Best regards,
Cary 

---
Cary Renquist
cary.renquist at ezag.com


-----Original Message-----
From: radsafe-bounces at health.phys.iit.edu [mailto:radsafe-bounces at health.phys.iit.edu] On Behalf Of Vernig, Peter G.
Sent: Friday, 16 July 2010 08:59
To: ROY HERREN; jearadrat at aol.com; radsafe at health.phys.iit.edu
Subject: Re: [ RadSafe ] Cl-36 in Nuclear Medicine?

Things have hit around this but I do not believe anybody has stated that Cl-36 is not a positron emitter, it decays primarily by beta emission like 98% and 1% or so electron capture.  So unless something pretty unusual is being done...

 Any opinions in this e-mail are solely those of the author, and are not represented as those of the VA Eastern Colorado HCS, the Dept. of Veterans Affairs, or the US Government.

Peter G. Vernig,RSO

-----Original Message-----
From: radsafe-bounces at health.phys.iit.edu [mailto:radsafe-bounces at health.phys.iit.edu] On Behalf Of ROY HERREN
Sent: Friday, July 16, 2010 9:56 AM
To: jearadrat at aol.com; radsafe at health.phys.iit.edu
Subject: Re: [ RadSafe ] Cl-36 in Nuclear Medicine?

Another PET isotope that is interesting is Rubidium Rb 82, see 
http://www.cardiogen.com/.  The half life of Rb82 is only 75 seconds.  The 
isotope literally goes directly from the generator into an IV and the on into 
the patient who is laying on the PET scanner gantry.
 Roy Herren 




________________________________
From: "jearadrat at aol.com" <jearadrat at aol.com>
To: radsafe at health.phys.iit.edu
Sent: Thu, July 15, 2010 2:04:34 PM
Subject: [ RadSafe ] Cl-36 in Nuclear Medicine?



Good afternoon, all:

In a reqcent company training session, one of my fellow technicians mentioned 
that a nuclear medicine application was being developed for chlorine-36.  
Considering the VERY long (3E5 yrs) half-life, what possible patient application 
can there be for this?  Or is it possible some erroneous information is being 
spread?

Thanks in advance,
John Aperans, RRPT
Clinton, TN USA


P.S. Please be gentle, this is my first post.
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