[ RadSafe ] MRI as a tool to assess local radiation-induced damage

[HOWARD.LONG at comcast.net]

Not only MRI but also CT (yes, more radiation!) should be considered 

to evaluate severe local radiation damage. 

Bobby Scott shook us up at a DDP meeting with data suggesting that 

low dose radiation reduced damage after rad overdose. Counter intuitive! 

Bobby, would you comment? 



Howard Long 



----- Original Message ----- 
From: "Brian G Rees" <brees at lanl.gov> 
To: "Nils Rudqvist" <nils.rudqvist at gmail.com>, radsafe at health.phys.iit.edu 
Sent: Monday, May 3, 2010 7:52:55 AM GMT -08:00 US/Canada Pacific 
Subject: Re: [ RadSafe ] MRI as a tool to assess local radiation-induced damage 

IAEA STI/PUB 1106 (THE CRITICALITY ACCIDENT IN SAROV) Discusses the use of CT scans in assessing the victim's condition... 

Brian Rees 

-----Original Message----- 
From: radsafe-bounces at health.phys.iit.edu [mailto:radsafe-bounces at health.phys.iit.edu] On Behalf Of Nils Rudqvist 
Sent: Wednesday, April 28, 2010 9:12 AM 
To: radsafe at health.phys.iit.edu 
Subject: [ RadSafe ] MRI as a tool to assess local radiation-induced damage 

Dear radsafers, 

I have been reading the TMT Handbook (Triage, Monitoring and Treatment), 
http://www.tmthandbook.org/. I found the following text in a chapter 
regarding local radiation-induced damage: 

"Magnetic resonance imaging (MRI) can be useful in detecting damage in 
deeper tissues e.g. muscle. Since MRI may demonstrate oedema and 
inflammatory reactions extending well beyond the lesion, these signs cannot 
be used alone to guide surgery.", 

This can be found on page 291 in the handbook, where they also point to an 
article of Peter and Gottlober (2002) as the reference. I have troubles 
finding this article and to be honest, i have a hard time finding anything 
at all about the clinical use of MRI as an dosimetric instrument. Of course, 
one could use MRI to detect lesions and so on, but has it been done? And if 
it has been used, to what grade - what absorbed doses could one "detect". 

There is some litterature supporting the use of MRI and MRS to look at 
higher doses, i.e. lesions in the brain after external radio therapy, but if 
one wanted to use MR as a tool to find and do dose-asessments, i dont know 
if that is a good idea... 

I request your help! If anyone out there have experience of using MR as a 
tool for dose-asessment or might know anything at all about it, please 
contact me. 

Thanks, 

Nils Rudqvist 
Gothenburg, Sweden 
_______________________________________________ 
You are currently subscribed to the RadSafe mailing list 

Before posting a message to RadSafe be sure to have read and understood the RadSafe rules. These can be found at: http://health.phys.iit.edu/radsaferules.html 

For information on how to subscribe or unsubscribe and other settings visit: http://health.phys.iit.edu 
_______________________________________________ 
You are currently subscribed to the RadSafe mailing list 

Before posting a message to RadSafe be sure to have read and understood the RadSafe rules. These can be found at: http://health.phys.iit.edu/radsaferules.html 

For information on how to subscribe or unsubscribe and other settings visit: http://health.phys.iit.edu