[ RadSafe ] Fwd: Effective half life question

[Chris Alston]

Jerry

It is "effective" in that it is a means of combining the physical t1/2
and the biological t1/2 into a single term, or value, thus much
simplifying calculations (and intuitions).  The formula is (please
forgive my use of plain text): Tb x Tp / Tb + Tp = Teff, where Tb =
biological half-life, Tp = physical half-life, and Teff = effective
half-life.  It should be written more elegantly as "T sub b" etc.

Cheers
cja


---------- Forwarded message ----------
From: Jerry Cohen <jjc105 at yahoo.com>
Date: Thu, Oct 25, 2012 at 4:07 PM
Subject: Re: [ RadSafe ] Effective half life question
To: "The International Radiation Protection (Health Physics) Mailing
List" <radsafe at health.phys.iit.edu>


What is the "effect" that effective half-life relates to?



________________________________
From: Cary Renquist <cary.renquist at ezag.com>
To: The International Radiation Protection (Health Physics) MailingList
<radsafe at health.phys.iit.edu>
Sent: Wed, October 24, 2012 2:25:04 PM
Subject: Re: [ RadSafe ] Effective half life question

The RADAR site has an excel sheet with biokinetic info on many
radiopharmaceuticals
http://www.doseinfo-radar.com/RADARHome.html
This is the direct link to the excel sheet:
http://www.doseinfo-radar.com/NMdoses.xls


---
Cary Renquist
cary.renquist at ezag.com


-----Original Message-----
From: radsafe-bounces at health.phys.iit.edu
[mailto:radsafe-bounces at health.phys.iit.edu] On Behalf Of Kulp, Jeffrey
(DOH)
Sent: Wednesday, 24 October 2012 12:00 PM
To: radsafe at health.phys.iit.edu
Subject: [ RadSafe ] Effective half life question

Hello Radsafers,



I have a question that is related to radiopharmaceuticals. I have been
told by a colleague that the effective half-life of a radioactive
isotope can differ based on the chemical preparation the isotope is in.
Essentially the biological half life will change due to the varying
clearance rates for different chemicals, thereby changing the effective
half-life. Is there a database that addresses the different biological
half-lives for various radiopharmaceuticals?



Thanks,



Jeffrey Kulp, RRPT

Radiation Health Physicist

DOH - Office of Radiation Protection

P.O. Box 47827

Olympia, Washington  98504-7827

(360) 236-3237

"Public Health - Always Working for a Safer and Healthier Washington"





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