[ RadSafe ] Cancer Genesis
JPreisig at aol.com
JPreisig at aol.com
Sun Jul 13 11:34:16 CDT 2014
Here is one model of cancer creation. It was asked on Radsafe if
cancer cells form from normal human cells or is some other process involved.
Other processes might be teleportation of cancer cells into the body or
perhaps generation of these special (cancer) cells by the body as a response
to some carcinogen.
For the moment I will assume that cancer cells are created from normal
human cells in the presence of some carcinogen. If this is not the case,
then the model I present fails.
A normal human cell in a pristine or normal environment has water and
oxygen and other nutrients present for growth. The cell grows at a normal
rate and is pretty happy.
If such a normal cell finds itself in a surrounding environment with
carcinogens present (at some percentage normal watery environment versus
carcinogen environment) then matters change. Some structural or chemical or
whatever process has caused carcinogen concentration to be something well
beyond normal. Let's say the cell is awash in a high concentration of
carcinogen. How does the cell respond to this??? The cell's programming is
stored in its DNA, perhaps.
Since the cell is now awash in some carcinogen, it will have a hard
time finding sufficient nutrients, oxygen etc. for growth. The degree of
response by the cell may depend on the concentration of the carcinogen. The
normal cell is now in a stressed situation. If it cannot get enough
nutrients it will die or be damaged.. Perhaps one response of the normal cell is
to grow its cell walls quickly in order to get more and proper nutrients.
Sound like rapid cancer growth, doesn't it??? Another response by the
cell is to cycle nutrients (by diffusion, osmosis etc.) more quickly, thus
incorporating more carcinogen into the cell. Not good. One could envision
other similar processes as exposure to the carcinogen continues.
As the cell continues to try to respond to the carcinogen, one could
envision a fair number of scenarios by which the carcinogen incorporation
process proceeds. Cell nuclear matter could be damaged. The cell could try
to reproduce by cellular fission, and thus more cells responding to the
carcinogen are produced.
Some of the normal cells start to die. Again sounds like cancer.
I am not a biologist either, but I did well in the course I took on
Radiation Biophysics. Thank You, Alan Appleby of Rutgers University. This
email is just a brief answer to the question posed on Radsafe. Systems
Engineering, Kalman Filtering etc. might be used to describe the actual cancer
production process. The devil is in the details I guess. I could go on
further about all this but it is early in the day and no one is paying me to
do all this right now. Eric Hall's book on Radiation Biology/Biophysics is
a good source of information, even if I don't have a recent edition.
You all have a good week at work or at home.
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