[ RadSafe ] DNA can be damaged by very low-energy radiation

Mohan Doss mohan.doss at fccc.edu
Fri Mar 14 12:41:38 CDT 2014


I contacted the author, and he said it is tentatively scheduled to be 
published Mar 21 in Physical Review Letters.  I also questioned his 
decision to release it to news media before its publication.

Mohan Doss, Ph.D., MCCPM
Medical Physicist,
Associate Professor, Diagnostic Imaging,
Fox Chase Cancer Center,
333 Cottman Avenue,
Philadelphia, PA 19111-2497.
Phone: 215 214-1707
Website: http://www.fccc.edu/research/pid/doss/
Blogs: http://mohan-doss-home-page.blogspot.com/


On 3/14/2014 12:15 PM, parthasarathy k s wrote:
> Dear Roy Herren,
>
> I made a mistake in the following statement.
>
> "I am unable to understand why the researchers did not publish the results in a peer journal before making it public." 
>
> The correct statement is:
>
>
> "I am unable to understand why the researchers did not publish the results in a peer reviewed journal before making it public."
>
>
> I am sorry for the mistake
>
>
>
>
> On Friday, 14 March 2014, 14:41, parthasarathy k s<ksparth at yahoo.co.uk>  wrote:
>
> Dear Dr.Roy Herren,
>
> This EurekAlert news release is issued by Tata Institute Of Fundamental Research(TIFR), Mumbai. TIFR is considered to be the cradle of all nuclear energy developments in India.
>
> I am unable to understand why the researchers did not publish the results in a peer journal before making it public. Am I missing something here?. Their discovery seems to be novel.The general impression is that such low energy photons are not energetic enough to create double strand breaks.
>
> Warm regards
> Parthasarathy
>
>
>
>
>
>
>
> On Friday, 14 March 2014, 13:21, ROY HERREN<royherren2005 at yahoo.com>  wrote:
>
> PUBLIC RELEASE DATE:14-Mar-2014 Contact: Deepak Mathur
> atmol1 at tifr.res.in
> 91-222-278-2736
> Tata Institute of Fundamental Research
>
> DNA can be damaged by very low-energy radiation
> How safe are 'eye-safe' lasers?
> "Very low-energy radiation also damages DNA: how safe are "eye-safe" lasers?"
> Damage to DNA by high energy radiation constitutes the most lethal
> damage occurring at the cellular level. Surprisingly, very low-energy
> interactions - with OH radicals, for instance - can also induce DNA
> damage, including double strand breaks. It is known that single strand
> breaks in the DNA backbone are amenable to repair but most double strand breaks are irreparable. The propensity with which slow OH
>   radicals
> damage DNA depends on their rotational energy: rotationally "hot" OH
> is more proficient in causing double breaks. These novel findings are
> from experiments conducted on DNA in a physiological environment.
> Intense femtosecond laser pulses are propagated through water (in which
> DNA plasmids are suspended), creating plasma channels within water,
> resulting in
> generation, in situ, of electrons and OH radicals. It is shown that use
> of long laser wavelength light (1350 nm and 2200 nm) ensures only
> OH-induced damage to DNA is accessed. It is noteworthy that industry
> presently characterizes as "eye-safe" lasers that emit at wavelengths
> longer than 1300 nm.
> But it is such wavelengths that are proficient at inducing damage to DNA: how safe is "eye-safe" when DNA in the eye can be readily
> damaged?
> ###
>
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