LD/50 for rats and humans

[james.g.barnes@att.net]

Dear Brian,

Yes, that certainly couldn't be a fun experience.

However, from what I can gather, they anticipated that 
the exposure environment would be somewhat challenging, 
and they controlled for it (both pre- and post-exposure).  
Net result appears to be that the exposure room did not 
induce an aversion reaction, just the radiation did.

Jim
> Jim,
> 
> I'm curious about the methodology used, from pictures I've seen that show
> the exposure apparatus for rats (mice, etc.),  you'd invoke an aversion
> response in me too after being placed in an (scaled) exposure chamber a few
> times.  :  ( )   If there were no "placebo" exposures I'd start to question
> the results.   
> 
> Brian Rees
> brees@lanl.gov
> 
> 
> >Specifically, I have been reviewing a paper written in 
> >1967 that demonstrates that rats would avoid flavored 
> >water that they had been conditioned to associate with 
> >low levels of radiation exposure.  Specifically, doses of 
> >10 - 50R (independent of dose rate) were cited as 
> >adequate to induce this aversion response.  What would 
> >this be in "human rem?"
> >
> >Thanks in advance,
> >
> >Jim Barnes, CHP
> >Radiation Safety Officer
> >Rocketdyne/Boeing
> >james.g.barnes@att.net
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information can be accessed at http://www.ehs.uiuc.edu/~rad/radsafe.html