Re: Long-Term Genomic Instability in Human Lymphocytes Induced by

[Emil Murat <kerrembaev@yahoo.com>]

Greetings,

I have tried to get a copy of the abstract via link
which was posted but it did not work....

So just by reading the original posting, I have a few
questions:

1. How "clean" was the experiment?
What was the background radiation?
(I hope, they did not have a radioactive source stored
on the next table).

2. For how long was observed the "Long-Term Genomic
Instability in Human Lymphocytes" ?
I am interested in the word " LONG "

3.What is the real time ? 

Population doublings is a relative time

1213 population doublings =.... ? days, years-? 

4. How rapid the cell division?

5. How sustainable the "Instability"?
Only 1213 population doublings what after that?

6. Are those aberrations increased and then decreased
below Detectable Level?
Or they were always increasing? What is the function?

This article is sounding to me, little bit.........
like the "FUSION reports":
"We got SUSTAINABLE fusion for so many micro
seconds..."
"We got SUSTAINABLE fusion for so MANY mills of second
and it gave us BACK a some energy...."

I DO understand the necessity to do SOME experiments
and experiments indeed are needing those MONIES. 
May be....., I would do the same thing if I were them.

But there is NO reason to report that NOW we ALMOST
GOT IT!

It is not a new thing that alpha particle indeed has a
high LET as well as other heavy charge particles and
of course it releases more energy per unit of length
i.e. cause more damage to a cell structure.

7. I have some doubts about a "NEW" in the study.

If they used a new method to
separate/measure/interpolate/calculate energy 
which alpha particle transfers along and the results
are showed that it is indeed a some high LET and
damage/aberrations are sustain for a time/1213 
population doublings. 
Good job!

But,

I do not see anything SIGNIFICANT in those findings
but a nice performed experiment gives a NUMBER for how
long the damage/chromatid-type 
aberrations are sustaining after alpha particle
interacted.


8. The only NEW information I can see is in terms of
updating the Quality Factor's value for Alpha
Particles.
Now, there is QF of 20.

9. Do you think it is should be lesser or higher?

Or may be you DO have a PROVE that ONE alpha particle
will indeed can cause the CANCER?

Don't you think that particles with a high LET, like
alphas will eventually JUST kill the cell? 
Therefore layer of DEAD cells will be an absorbing
material for the following alpha particles and work as
a shielding?

Self shielding?
Think about it......

My personal experience: 
I did observe a few persons with high quasi-acute
TOABD's (Total Absorbed Body Dose), a few hundreds of
Rads in periods of weeks, and they indeed had
developed sever clinical forms of vascular
fibroses...and....

On the other hand:

The "recent" approval, by USFDA of a treatment for
post cardio-vascular surgery complications with a
quasi-acute dose of radiation, is saying something.


So, What is that saying?

It is good for you, if you use it properly.
And vice versa.

Don't you think, the nature is much smarter than we
sometimes think of it?
And it deserves more credits.

A safe weekend for everyone.

Respectfully,

Emil.


You wrote:
>>>
surviving progeny of cells. A 
significant increase in the proportion of aberrant
cells is observed 1213 
population doublings after exposure, with a high level
of chromatid-type 
aberrations, indicative of an instability phenotype.
These data suggest 
that instability may be important in situations where
even a single 
particle traverses human cells.
>>



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