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Re: Hormesis?

Although I didn't follow the complete discussion. If there are beneficial, 
effects they can be due to the activation of a specific group of genes 
which expression result in the "beneficial effects" observed with different 
types of radiation. This expression can be the so-called stimulatory 
effects that after the exposure will last for a specific period and can be 
specific for a cell type, an organ or even the mitochondria and ribosomal 
apparatus.

The complexity of the process can be due to different genes activated by 
different radiations. If this is the case, hormetic effects can result in 
the increase of the incidence of cancer?


Willy A. Valdivia
Plant Sciences Dept.
North Dakota State University


--On Tuesday, February 13, 2001 12:46 AM -0600 Christoph Hofmeyr 
<Christoph_Hofmeyr@nnr.co.za> wrote:

>
> Radsafers,
> Thanks for several comments to my query, implying the same, namely
> simultaneous detrimental as well as beneficial effects, obviously as a
> function of dose.  I think an important and valid question is whether the
> two effects are coupled or uncoupled.  Bernie seems to imply that the two
> are coupled and the benefit will therefore cancel the detriment (at least
> in a certain dose range).  However, should the effects be weakly- or
> un-coupled, the detriment can persist with a certain probability and
> result in a 'stochastic' effect in due course.   Do we understand the
> mechanisms well enough to decide?  My own thoughts.
> Chris Hofmeyr
> chofmeyr@nnr.co.za
>
>
> You wrote:
>
>
> 

>                     Bernard L Cohen
>                      <blc+@pitt.edu>           To:     Multiple
>                     recipients of list                Sent by:
>                     <radsafe@romulus.ehs.uiuc.edu>
>                     radsafe@romulus.eh        cc:     (bcc: Christoph
>                     Hofmeyr/CNS1)              s.uiuc.edu
>                     Subject:     Re: Hormesis?
> 

> 

>                     2001/02/09 17:01
>                      Please respond to
>                      radsafe
>
> 

> 

> 
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