Re: Hormesis?

[Muckerheide <muckerheide@mediaone.net>]

Dr.  Surveyor,

A widely recognized and highly regarded paper on the subject, including
methodological aspects, by John Ward who has been mentioned here, is:

Prog Nucleic Acid Res Mol Biol 1988;35:95-125
DNA damage produced by ionizing radiation in mammalian cells: identities,
mechanisms of formation, and reparability.
Ward JF
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list
_uids=3065826&dopt=Abstract

The results were more directly related to the issues here by Dan Billen in
Radiation Research:

Radiat Res 1990 Nov;124(2):242-5
Spontaneous DNA damage and its significance for the "negligible dose"
controversy in radiation protection.
Billen D
Oak Ridge Associated Universities, Medical Sciences Division, Tennessee
37831-0117.
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list
_uids=2247605&dopt=Abstract

Regards, Jim
muckerheide@mediaone.net
==========================

> To Radsafe,
> 
> Chris Hofmeyr is not alone in finding  all this talk about DNA and DNA
> breaks etc. as being somewhat daunting.
> It is very interesting and important material.   But how do the radiation
> biologists  determine the rate of different types of DNA breaks per cell
> per day for example?
> Ivor Surveyor [isurveyor@vianet.net.au]
> Emeritus Consultant Physician
> Nuclear Medicine
> Royal Perth Hospital
> 
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