LNT, SNT, or whatever

["Harry Hinks" <harryhinks@hotmail.com>]

Dr. Cohen,

I was just suggesting that the reason some journals do not publish the 
studies Mr. Muckerheide referred to is because they may have used summary 
data.

But, getting back to your point - I would think there are better ways of 
testing the LNT than using summary data.  Cellular level studies would 
appear to have much more control over variables that may influence the 
outcome.  I imagine there are many variables that you have little control of 
when using summary data.  To control these variables, you would be dependent 
on using more summary data as a means of control. Dr. Raabe previously 
mentioned that you could not take into account the summary level bias.  
Until you are sure you can take care of this bias, does it matter if the 
model is LNT or SNT (sigmoidal)?

Harry Hinks
harryhinks@hotmail.com




	--My study was a test of the linear-no threshold theory (LNT), and 
according to LNT, the average dose determines the mortality rate. There is 
no need to measure radon in individual homes unless you are willing to 
abandon LNT. If you will propose an alternative to LNT, I would be glad to 
test whether it supports hormesis.

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