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Re: Re: Source of cancer data
John,
Epideiologists who would choose Field's Iowa incidence in 431 over
Cohen's
mortality in 100,000 plus (showing such consistent results), must be
inexperienced.
Howard Long MD MPH, Family Doctor and Epidemiologist
363 St. Mary St., Pleasanton CA, 94566
(925) 846-4411, Fax 4524, Page 787-0253 hflong@pacbell.net
John,
If I were pressed to choose between your experience and the
experience of the following individuals, I think I would choose them.
I think this site supports my view.
http://www.cheec.uiowa.edu/misc/radon.html
COMMENTS FROM OTHER SCIENTIST
"The Iowa Radon Lung Cancer Study, conducted by Drs. R. William
Field, Charles F. Lynch and colleagues represents by far the most
substantial study of residential radon health effects accomplished to
date. By rigorous analysis of radon exposures for women with lung
cancer and matched controls, this study has shown a clear association
between lung cancer and radon exposures in homes.
A major advantage of this study was the high radon levels found in
Iowa homes, which showed about a 50% increase in lung cancer risk at
the EPA action level of 4 pCi/L. The Iowa lung Cancer Study is a
major milestone for confirming lung cancer incidence due to radon
exposures as predicted by the National Academy of Sciences BEIR VI
report. The researchers should be highly commended for this
definitive study showing substantial lung cancer risks due to radon
exposures in homes."
Raymond Johnson, Certified Health Physicist
Past-President, Health Physics Society
---------------------------------------
Dear Bill,
"I wanted to commend you and the other investigators on the Iowa
Radon Lung Cancer Study. I believe the methods you used to reduce the
inherent random error associated with ascertaining long-term
residential radon exposure are critical to validly assessing the lung
cancer risk from this source. As you correctly point out the random
error in estimating radon exposure has the potential to substantially
underestimate the slope of the dose-response curve. Your estimates of
risk are similar to my own in our study of lung cancer among Missouri
women, where we used historic estimates of radon exposure from
cumulative measures of radon progeny in glass.
I believe that most studies published to date have been ineffective
in reducing measurement error and their dose-response results have
suffered from a bias toward the null. I look forward to the
discussion your results will generate and urge you to complete the
analysis of you radon progeny in glass measurements data. Along with
your current manuscript, that data should help clarify the true
nature of the dose-response curve between residential radon and lung
cancer risk. Again congratulations on a job well done."
Sincerely,
Michael Alavanja, Dr.P.H.
Senior Investigator,
Division of Cancer Epidemiology and Genetics
Rockville, M.D. 20892
--------------------------------------
"The Iowa Study is a significant addition to our already strong
understanding of indoor radon and lung cancer. Its particular
importance lies in the careful methodologic work done by the
investigators on some nagging scientific issues--particularly the
estimation of lifetime exposure to radon."
Dr. Jon Samet
Professor and Chairman
Department of Epidemiology
School of Hygiene and Public Health
Johns Hopkins University
Suite 604l
615 N. Wolfe Street
Baltimore, Maryland
-------------------------------------------
U.S. ENVIRONMENTAL PROTECTION AGENCY VIEW OF THE STUDY
The Iowa study is exceptionally well designed and well executed. It
adds to the body of knowledge, which designates residential radon as
the second leading cause of lung cancer. It supports EPA's position
and the National Academy of Sciences' Institute of Medicine's 1999
report that radon exposure in homes is a public health problem. It
confirms EPA's, the Center for Disease Control's, and the Surgeon
General's positions that all homes should be tested for radon, and
all homes testing over 4 pCi/L should be fixed. In terms of
scientific advancements, the study breaks new ground in estimating
total individual radon exposure.
See EPA web site:http://www.epa.gov/iaq/radon/
Sent by Law Mail
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