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Re: radon and smoking



Ruth,

Radon-222 progeny is another name for the
222Rn decay products or 222Rn daughters. Radon-222 progeny rather than 222Rn gas deliver the actual radiation dose to lung tissues. The solid airborne 222Rn progeny, particularly 218Po, 214Pb, and 214Bi, are of health importance because they can be inspired and retained in the lung. The radiation released during the subsequent decay of the alpha-emitting decay products 218Po and 214Po delivers a radiologically significant dose to the respiratory epithelium. The ratio of progeny to 222Rn gas ranges from 0.2-0.8 with a typical value of 0.4. The ratio between progeny and 222Rn gas is called the equilibrium factor.

After decay of the
222Rn gas, a high percentage of the decay products attaches to ambient aerosols. A small percentage of the decay products remains unattached; others increase their diameter through chemical and physical processes. The percent attachment depends on numerous factors, including the size and concentration of the airborne particles. The size and density of a particle determine its behavior in the respiratory tract. The unattached particle fraction with a 1-nm diameter is generally removed in the nose and mouth during breathing and has limited penetration of the bronchi. Maximal deposition occurs as the particles with diameters ranging from 3-10 nm increase their rate of penetration through the mouth and nose, ultimately depositing in the bronchial region. The deposition rate decreases for particles as their diameter increases toward 100 nm and larger because the particles are less able to diffuse to the airway surface. However, particle deposition into the respiratory tract through impaction starts to increase again for particles above 500 nm. Larger particles with a diameter exceeding 3.5 µm deposit predominantly in the nose and mouth during inhalation and do not reach the sensitive respiratory epithelium.


SEE ALSO: http://www.vh.org/Providers/Textbooks/Radon/HealthRisk.html

Regards, Bill












At 01:33 PM 2/13/2002 -0500, you wrote:
In a message dated 2/13/02 9:57:34 AM Mountain Standard Time, bill-field@UIOWA.EDU writes:


In your email below, you did not mean to imply that the radon GAS
concentrations increased did you?  I would expect the aerosols and airborne
radon progeny to increase, but not the radon gas concentrations.


I do not understand this question.   Radon is chemically inert.  If damage to the lung alveoli is from the radon alpha, what difference does it make if it is carried into the lung as a gas on loosely bound to a particle.  Is the difference in the residence time in the lung?  Is the difference that radon progeny would be more likely to stay in the lung if the radon is on a particle?


Ruth Weiner, Ph. D.
ruthweiner@aol.com

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