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Fw: I-131 in Pregnancy and Abortion
I strongly agree with Otto's referral to Dr. Brent. You can also see some
related issues that Dr. Brent and others have already addressed on this
topic at the HPS' Ask the Expert site
(http://hps.org/publicinformation/ate/cat4.html).
The dose to the fetus in this case will depend somewhat on the degree of
hyperthyroidism, but I estimate it at 20-35 mGy (2-3.5 rad), using the table
at the RADAR site (http://www.doseinfo-radar.com/RADAR-INT-NM.html) (and
assuming you meant "millicuries" by "mc"). The ICRP's latest
recommendations (ICRP 84) say that fetal doses less than 100-200 mGy (10-20
rad) do not justify consideration of terminating the pregnancy because of
the radiation exposure; this is consistent with recent recommendations by
the NCRP as well.
Mike
Michael G. Stabin, PhD, CHP
Assistant Professor of Radiology and Radiological Sciences
Department of Radiology and Radiological Sciences
Vanderbilt University
1161 21st Avenue South
Nashville, TN 37232-2675
Phone (615) 343-0068
Fax (615) 322-3764
e-mail michael.g.stabin@vanderbilt.edu
internet www.doseinfo-radar.com
>
> ----- Original Message -----
> From: "Otto G. Raabe" <ograabe@ucdavis.edu>
> To: <radsafe-owner@list.vanderbilt.edu>
> Cc: "Moshe Levita" <mlevita@netvision.net.il>
> Sent: Monday, August 19, 2002 1:47 PM
> Subject: Re: I-131 in Pregnancy and Abortion
>
>
> > At 06:58 PM 8/19/02 +0200, MOSHE LEVITA wrote:
> > >A 23 year old woman received 14.6 mc I-131 for hyperthyroidism.
> > >A few days later it became apparent that she had conceived one week
> before
> > >receiving the I-131.
> > >
> > >In other words the 14.6 mc were given in her 1-2 first weeks of
> pregnancy.
> > >She is now 5-6 weeks pregnant.
> > >
> > >Should abortion be considered in view of possible damage to the fetus ?
> > >
> > >Your fast opinion is very important.
> > >
> > >Moshe Levita
> > >Ministry of Health, Israel
> > >mlevita@netvision.net.il
> > >
> > >Mobile: 972-64-266536
> > *************************************************
> > August 19, 2002
> > Davis, CA
> >
> > It is not clear that the embryo received any significant dose since the
> > iodine is rapidly taken up by the mother's thyroid and the young embryo
> has
> > no thyroid.
> >
> > The world's expert on this issue is Dr. Robert L. Brent, head of the
> > teratology lab at the Alfred duPont Institute in Wilmington, DE.
E-mail
> > him at rbrent@nemours.com
> >
> > Otto
> > *****************************************************
> > Prof. Otto G. Raabe, Ph.D., CHP
> > Center for Health and the Environment (CHE)
> > (Street address: Building 3792, Old Davis Road)
> > University of California, Davis, CA 95616
> > Phone: 530-752-7754 FAX: 530-758-6140
> > E-mail ograabe@ucdavis.edu
> > *****************************************************
>
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