Re: Low dose stimulation produces immunity to cancer

[Muckerheide <muckerheide@attbi.com>]

on 10/26/02 1:19 AM, Bjorn Cedervall at bcradsafers@HOTMAIL.COM wrote:



>> J. B. Murphy (Proceedings of the National Academy of Sciences), studying

>> cancer immunity and the role of lymphocytes, reports that both natural and

>> induced immunity controls and destroys cancers in mice (specific cancers in

>> a specific strain), and that lymphocytes target and destroy those tumors.

>> He shows this by using the property of small doses of x-rays to suppress

>> lymphocytes. As lymphocytes are suppressed, the tumors are increasingly

>> able to become established and to grow rapidly.

> 

> But, he reports that their finding that at even lower doses the lymphocytes

> are NOT suppressed, but stimulated!

> ---

> 

> Referring to the last sentence - what exactly is meant by stimulation?



Bjorn,



Two factors:

First, an simple increase in the number of lymphocytes per mL;



Second, a faster and more successful attack on the induced tumor (or

infection).



Did you retrieve the paper? It's just 4 pages. There are a few other papers

from the period there also that are more definitive and descriptive on

immune response to cancer.



Thanks,

Regards, Jim

 

> Bjorn Cedervall   bcradsafers@hotmail.com

> ---

> PS. Radiation victims: About ten hours ago I gave a reference (from 1902) to

> a tumor in an X-ray ulcer but it hasn't showed up yet. Wonder why.

> 

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