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Re: NRC PROPOSES $6,000 FINE



> To estimate the dose to the patient, I recommend reviewing NCRP Report No.

70,

> "Nuclear Medicine - Factors Influencing the Choice and Use of

Radionuclides in

> Diagnosis and Therapy."



If you mean dose FROM the patient, one should not rely on this 1982 NCRP

document. This has been the subject of much recent discussion since the

release of NRC Reg Guide 8.39 in 1997. Besides the Reg Guide, I recommend

the following reading:



Jeffry A. Siegel, Carol S. Marcus, and Richard B. Sparks, Calculating the

Absorbed Dose from Radioactive Patients: The Line-Source Versus Point-Source

Model. J. Nucl. Med. 43: 1241-1244, 2002.

Pat B. Zanzonico, Jeffry A. Siegel, and Jean St. Germain a generalized

algorithm for determining the time of release and the duration of

post-release radiation precautions following radionuclide therapy. Health

Physics 78(6): 648; Dec 2000



Richard B. Sparks, Jeffry A. Siegel, and Richard L. Wahl the need for better

methods to determine release criteria for patients administered radioactive

material. Health Physics 75(4): 385; Dec 1998.



There is other good reading in the J Nucl Med about release criteria for

patients receiving therapy with other compounds. If you really meant dose TO

the patient, presumably the thyroid, one would use a standard MIRD

formulation, but often knowledge of the thyroid mass (or remnant mass) and

effective half-time are not known.



Mike



Michael G. Stabin, PhD, CHP

Assistant Professor of Radiology and Radiological Sciences

Department of Radiology and Radiological Sciences

Vanderbilt University

1161 21st Avenue South

Nashville, TN 37232-2675

Phone (615) 343-0068

Fax   (615) 322-3764

Pager (615) 835-5153

e-mail     michael.g.stabin@vanderbilt.edu

internet   www.doseinfo-radar.com





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