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Avoidance of reactions to radiocontrast media?

Hi all:

A thread on Radsafe recently discussed allergic reactions to contrast 

agents used in certain imaging procedures. A note was posted to Medscape 

recently to the following relevant

question which may be of interest to some involved in medical HP or who 

might be involved in evaluating a procedure they or a family member may 

need to receive.



Stewart Farber

=====================

Allergic Reactions to Radiocontrast Media

<url: http://www.medscape.com/viewarticle/463963>



Question:

What are the guidelines on the incidence and avoidance of reactions to 

radiocontrast media?



Emilia Galea



Response from Bradley E. Chipps, MD, FCCP Medical Director, Cystic Fibrosis 

Center, Capital Allergy & Respiratory Disease Center, and Associate Medical 

Director, Sleep Laboratory of Sutter Community Hospitals, Sacramento, 

California



The guidelines for pretreatment of radiocontrast allergy have been 

published in the literature.[1-3] The nonionic dyes are less likely to 

cause a systemic reaction than the ionic solutions. This reaction is not 

believed to be of an Ig E-mediated cause. Treatment with H1-and H2-blockers 

at appropriate therapeutic doses and prednisone 1 mg/kg given both 24 hours 

and 1 hour before the radiology procedure is usually sufficient to block 

the reaction. Montelukast 10 mg may also be added to this regimen.



Posted 11/25/2003

References



1. Hong SJ, Wong JT, Bloch KJ. Reactions to radiocontrast media. Allergy 

Asthma Proc. 2002;23:347-351. Abstract

2. Abbott MB, Levin RH. Anaphylactoid reactions to radiocontrast agents. 

Pediatr Rev. 2001;22:356.

3. Katayama H, Yamaguchi K, Kozuka T, Takashima T, Seez P, Matsuura K. 

Adverse reactions to ionic and nonionic contrast media. A report from the 

Japanese Committee on the Safety of Contrast Media. Radiology. 

1990;175:621-628. Abstract



-- 

 

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