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RE: Current Issue of BMJ



>From the paper:



BMJ  2004;328:19 (3 January),

"Effect of low doses of ionising radiation in infancy

on cognitive function in adulthood: Swedish population

based cohort study," 

 

Per Hall, Hans-Olov Adami, Dimitrios Trichopoulos,

Nancy L Pedersen, Pagona Lagiou, Anders Ekbom,

professor1, Martin Ingvar, Marie Lundell, and Fredrik

Granath



RESULTS: The proportion of boys who attended high

school decreased with increasing doses of radiation to

both the frontal and the posterior parts of the brain

from about 32% among those not exposed to around 17%

in those who received > 250 mGy. For the frontal dose,

the multivariate odds ratio was 0.47 (95% confidence

interval 0.26 to 0.85, P for trend 0.0003) and for the

posterior dose it was 0.59 (0.23 to 1.47, 0.0005). A

negative dose-response relation was also evident for

the three cognitive tests for learning ability and

logical reasoning but not for the test of spatial

recognition. 



CONCLUSIONS: Low doses of ionising radiation to the

brain in infancy influence cognitive abilities in

adulthood. 



--- alstonchris@netscape.net wrote:

> My original note was misleading.  The doses to the

> brain in the study cited were secondary to

> radiotherapy for cutaneous hemangioma, not from

> cranial CT.  Also, the original article is actually

> in the BMJ of 3 January.  The issue of 3 March

> contains responses to that paper, and you can easily

> hyperlink to it from those letters.  That, and my

> careless scanning of the various texts, was why I

> got lost.

> 

> Mea culpa

> cja

> 

> 

> 

> alstonchris wrote:

> >Folks

> >You might be interested in the issue of 6 March.

>  There are articles, and notes, on topics like

> doctors' response to radiation incidents, and a

> possible link between childhood cranial CT and adult

> cognitive impairment.  Is it my imagination, or do

> the Brits publish these kinds of pieces more often

> than USA journals?  Go to: bmj.bmjjournals.com.

> 

. . .



=====

+++++++++++++++++++

""A fanatic is one who cannot change his mind and won't change the subject."  Winston Churchill



-- John

John Jacobus, MS

Certified Health Physicist

e-mail:  crispy_bird@yahoo.com



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