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RE: Gardner Sellafield cluster [was : reply to Cedervall ]
>If you recall my message context, I was suggesting that uranium
accumulation in testicles explains the cancer incidence increase
in children of exposed fathers.
---
Emphasize the word "suggesting" above. If you suggested that - where is the
publication where you discuss these cancer clusters in the context of sites
where there are no nuclear activities, or nuclear activities where there are
no clusters?
The chain of events:
1. uptake
2. accumulation in the testes
3. DNA damage
4. sperm carrying damage winning the swim contest to fertilize an egg
5. the fertilized egg and subsequent embryo being unaffected (and not
aborted) by some mutation 6. that same mutation having enough of statistical
penetrance to appear as a detectable increase in cancer
you suggest is farfetched, considering alternative explanations - in
addition take a look at the corresponding RERF work. There is too much
biology you need to explain to establish your suggestion.
Childhood cancers are mainly ALL, brain tumors and lymphomas (the other
cancers are extremely rare and at least some of them have a genetic
component) . When you write "cancer" you thus also suggest that it is about
brain tumors and lymphomas - have those been discussed in the Sellafield
context?
My personal reflections only,
Bjorn Cedervall bcradsafers@hotmail.com
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