[ RadSafe ] Re: LDR extends lifespan, and immune competence (again,
still)
John Jacobus
crispy_bird at yahoo.com
Mon Apr 4 15:43:30 CEST 2005
Just out of curiosity, how were you going to identify
those who suffered from "radiation deficiency?" What
is the "optimum dosage," let alone what was the best
radionuclide?
--- jjcohen <jjcohen at prodigy.net> wrote:
> FYI, a few years ago there was a string on radsafe
> on the possibility of administering supplementary
> radioactivity to those with "radiation deficiency"
> in order to achieve "optimal dosage". In discussing
> the best radionuclide for the purpose, as I recall,
> those that tend to concentrate in single organs such
> as the radioiodines should be avoided. I don't think
> any consensus was reached on what the "best"
> radionuclide should be, but because of its uniform
> distribution, tritium would seem to be a good bet.
> ----- Original Message -----
> From: yuan-chi luan
> To: uniqueproducts at comcast.net
> Cc: shliu at iner.gov.tw
> Sent: Saturday, April 02, 2005 5:27 PM
> Subject: Re: LDR extends lifespan, and immune
> competence (again, still)
>
>
> Dear Dr. Caplan:
>
> I think any isotope might be ok, but should with
> long biohalf-live. Kondo ever analysed the dose in
> received by ever fisherman. There was a NUREG by
> NRC about the atomic bomb workers internal
> contaminated, the doses might be able found.
>
> Y.C Luan
> -----------------------------------------------
> originnal
> message--------------------------------------
>
>
> >From: "Jay Caplan" <uniqueproducts at comcast.net>
> >Reply-To: "Jay Caplan"
> <uniqueproducts at comcast.net>
> >To: "yuan-chi luan" <nbcsoc at hotmail.com>
> >Subject: Re: LDR extends lifespan, and immune
> competence (again, still)
> >Date: Sat, 2 Apr 2005 14:25:25 -0600
> >
> >Dr. Luan,
> >Which isotope were you considering and dosage?
> >Jay Caplan
> > ----- Original Message -----
> > From: yuan-chi luan
> > To: kazsakai at criepi.denken.or.ip
> > Cc: wlchen at ym.edu.tw ; tisechou at hotmail.com ;
> wpdeng at ms41.hinet.net ; t5rgwjvs at mail.4797.com.tw ;
> htkung at ms79.hinet.net ; nusta66 at hotmail.com ;
> nbcsocmong at yahoo.com ; pual0401 at yahoo.com.tw ;
> hjren at iner.gov.tw ; mlshen at ccms.ntu.edu.tw ;
> mcshieh at so-net.net.tw ; wuj at aruplab.com ;
> johntm.wu at msa.hinet.net ; slyao at ms47.hinet.net ;
> jingying at ms22.hinet.net ; mbrexchange at list.ans.org ;
> bogen at llnl.gov ; edwardc at schoolph.umass.edu ;
> cdn-nucl-l at mailman1.cis.McMaster.CA ;
> nuc-en at ecolo.org ; pfong at physics.emory.edu ;
> higsond at bigpond.net.au ; indianjrr at yahoo.co.in ;
> nrer at obninsk.com ; cns at cnnc.com.cn ;
> liuxr at bine.com.cn ; luan2k03 at yahoo.com.cn ;
> andre.maisseu at wanadoo.fr ; rad-sci-l at WPI.EDU ;
> singer at sepp.org ; R.wakeford at bnfl.com ;
> shliu at iner.gov.tw
> > Sent: Saturday, April 02, 2005 1:50 PM
> > Subject: FW: LDR extends lifespan, and immune
> competence (again, still)
> >
> >
> > Dear Dr. Sakai:
> >
> > You will remember Y.C. Luan when when you
> remember some one giving a Chinese dinner in Hawaii.
>
> >
> > I am glad to see your paper again. Your paper
> in Hawaii showed the low-dose-rate irrdiation of
> mice could reduce their skin tumor,thymic lymphumas,
> diabetes and sever autoimmune disease really given
> me tremendous impression. Radiation is not harmful
> as ICRP espected
> >
> > The low-dose-rate external radiation could
> immune a lot bad thing, I would like to give you a
> idea for you to think the possibility in testing
> with mice to have low-dose-rate of internal
> radiation by injection of some long-life radioactive
> isotope into the mice. The only trouble you have to
> treat the mice as radio-waste. The manhattan workers
> and the fishermen in Lucky Dragon 5 had quite high
> internal contamination, but they are not 25% died in
> cancers, they seemed to immunized. is it possibly
> to have immunization by injection? is it better to
> have immunity in the Co-60 contamianted apartments
> in Taiwan?
> >
> > Please give regards to Dr. Hattori
> >
> > Y.C. Luan
> >
> -----------------------------------------------
> original message--------------------------
> >
> >
> > >From: "Muckerheide, James" <jimm at WPI.EDU>
> > >To: <rad-sci-l at WPI.EDU>
> > >Subject: LDR extends lifespan, and immune
> competence (again, still)
> > >Date: Fri, 1 Apr 2005 11:41:00 -0500
> > >
> > >Friends,
> > >
> > >This paper is by our great friends Yasuhiro
> Ina and Kazuo Sakai at the CRIEPI
> > >Low Dose Radiation Research Center in Komae.
> > >
> > >I have not yet read the full paper. The
> journal contents may not yet be
> > >internet accessible. Let me know if you need
> it for review when it is
> > >available (or perhaps request it from
> Yasuhiro or Kaz, though they may also
> > >be waiting for the final published version
> :-).
> > >
> > >Regards, Jim Muckerheide
> > >Radiation, Science, and Health
> > >=====================
> > >
> > >Ina, Y. and Sakai, K.
> > >
> > >Further Study of Prolongation of Life Span
> Associated with Immunological
> > >Modification by Chronic Low-Dose-Rate
> Irradiation in MRL-lpr/lpr Mice:
> > >Effects of Whole-Life Irradiation.
> > >
> > >Radiat. Res. 163, 418-423 (2005).
> > >
> > >MRL-lpr/lpr mice carry a deletion in the
> apoptosis-regulating Fas gene that
> > >markedly shortens life due to multiple severe
> diseases. In our previous study
> > >(Radiat. Res. 161, 168- 173, 2004), chronic
> low-dose-rate gamma irradiation
> > >of mice at 0.35 or 1.2 mGy/h for 5 weeks
> markedly prolonged the life span,
> > >accompanied by immunological activation. This
> report shows that extension of
> > >the irradiation period to the entire life of
> the mice at the same dose rates
> > >improved survival further. The 50% survival
> time for untreated mice, 134
> > >days, was prolonged to 502 days by 1.2 mGy/h
> life-long irradiation. Also
> > >obtained were a time course and a radiation
> dose-rate response for the
> > >activation of the immune system as indicated
> by a significant increase in
> > >CD4(+) CD8(+) T cells in the thymus and
> CD8(+) T cells in the spleen and also
> > >by a significant decrease in CD3(+)
> CD45R/B220(+) cells and CD45R/B220(+)
> > >CD40(+) cells in the spleen. Drastic
> ameliorations of multiple severe
> > >diseases, i.e. total-body lymphadenopathy,
> splenomegaly and serious
> > >autoimmune diseases including proteinuria,
> and kidney and brain-central
> > >nervous system syndromes, were found in
> parallel with these immunological
> > >activations, with lifelong low-dose-rate
> irradiation being more effective
> > >than 5-week irradiation at low dose rates.
> > >
> > >
> _______________________________________________
> You are currently subscribed to the radsafe mailing
> list
> radsafe at radlab.nl
>
> For information on how to subscribe/unsubscribe and
> other settings visit:
> http://radlab.nl/cgi-bin/mailman/listinfo/radsafe
>
+++++++++++++++++++
"Embarrassed, obscure and feeble sentences are generally, if not always, the result of embarrassed, obscure and feeble thought."
Hugh Blair, 1783
-- John
John Jacobus, MS
Certified Health Physicist
e-mail: crispy_bird at yahoo.com
__________________________________________________
Do You Yahoo!?
Tired of spam? Yahoo! Mail has the best spam protection around
http://mail.yahoo.com
More information about the radsafe
mailing list