Re: info

["Gary H. Kramer" <gkramer@hpb.hwc.ca>]

On Wed, 17 Jul 1996 kaplan@bnl.gov wrote:

> We are examining the possibility of replacing a 24 hour composite urine
> sample with a single grab sample for plutonium bioassay.  Can a single
> grab sample at one point during the day be scaled up to a full day?  Does
> anyone use this value to determine body burden?  Physicians scale urine
> sample results by the creatinine level.  Can we also use creatinine?  Does
> plutonium excretion follow a diurnal cycle that would make one void,
> perhaps the first morning, more representative of the entire day?????
> 
> -- 
> -----------------------------------------------------------
> kaplan@bnl.gov
> -----------------------------------------------------------
> 
 
A much more sensitive bioassay immediately following an intake is fecal 
monitoring.  Have you considered this?  If not, why not?

Regards

-----------------------------------------------------------------------
| H   H   M       M   L	       Gary H. Kramer  		              |
| H   H   MM     MM   L        Head, Human Monitoring Laboratory      |
| H   H   M M   M M   L	       Canadian National Calibration Reference|
| H   H   M  M M  M   L	       Centre for In-Vivo Monitoring          |
| HHHHH   M   M   M   L	       775 Brookfield Road, Ottawa, Ontario   |
| H   H   M       M   L	       CANADA K1A 1C1			      |
| H   H   M       M   L	       Tel: 613 954 6668;  Fax 613 957 1089   |
| H   H   M       M   LLLLLLL  GKRAMER@HPB.HWC.CA	              |
-----------------------------------------------------------------------
|     http://www.hwc.ca/dataehd/English/rpb/environ/index.htm         |
-----------------------------------------------------------------------