Re: Abscopal effects on critical organs

["H. G Claycamp" <hgc2+@pitt.edu>]

While I don't have a paper at my finger tips, I can recommend that you
search the 1950s-1960s literature.  I recall a number of papers (that were
history even when I read them) dealing with abscopal effects.  

Good hunting. 
	-Gregg   hgc2+@pitt.edu

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - 
H. Gregg Claycamp, Ph.D., C.H.P. 
Assoc. Prof. and Assoc. Chair 
Dept. of Environmental and 
  Occupational Health 
University of Pittsburgh 
412-967-6524 FAX:  412-624-1020


On Thu, 15 Oct 1998, Dave Abbott wrote:

> Hello Radsafers:
> 
> I've been working on a project that involves predicting the quantities of
> airborne radionuclides that it would take to produce an acute lethality
> within 60 days.  This involves estimating how much immersion and inhalation
> it would take to produce a lethal dose to the bone marrow, small intestine,
> and lungs.  The calculations have included cross talk, i.e., transport of
> photons from noncritical organs to critical organs.  A reviewer insists
> that this approach is flawed because it doesn't take into account indirect
> effects.  Direct effects on a noncritical organ will influence the lethal
> dose on the critical organs.  I have been unable to find any data to
> substantiate or refute this abscopal effect on lethal doses.  Can anyone
> shed some light on this question, preferably with citations in available.  
> 
> Thanks,
> David Abbott
> Lawrence Livermore National Laboratory
> abbott@washops.llnl.gov
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