RE: I-131 Thyroid Uptake

[Karin Gordon <KGordon@exchange.hsc.mb.ca>]

Hi

I work in the nuclear medicine environment - just asked one of our NM
physicians - he said that our local "normal" range for a 24 hour I-131
thyroid uptake was 8 - 30% .  Obviously, 8% is on the low end, while 30%
is high, and some patients with those uptakes might be exhibiting some
clinical symptoms of hypothroidism and hyperthyroidism respectively.
So, in medicine remember that "normal" usually falls within some sort of
range of values, rather than a single absolute value. 


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Karin Gordon
Radiation Safety Office
Health Sciences Centre
GC-214, 820 SherbrookSt.
Winnipeg, Manitoba
CANADA  R3A 1R9

KGordon@hsc.mb.ca           or        KGordon@cc.UManitoba.ca

phone (204) 787-2903
fax      (204) 787-1313




>----------
>From: 	Michael McCarty[SMTP:MCCARTMJ@state.mi.us]
>Sent: 	January 27, 1999 12:07 PM
>To: 	Multiple recipients of list
>Subject: 	I-131 Thyroid Uptake
>
>Does anyone have references to suggest for answers to the following
>questions:
>
>What is the typical percent of a iodine intake (we happen to be concerned
>with I-131) that will be taken into the thyroid gland?  My 1972 copy of
>Shapiro, "Radiation Protection" says 30%, but there is some indication that
>it may be as low as 3% (at least for some individuals) according to other
>sources.
>
>So, is the answer a range, say about 3 to 30%?  Does the pathway make a
>difference, e.g. nuclear medicine injection vs. reactor release and
>subsequent accidental inhalation?
>
>Thanks,
>Mike McCarty
>Health Physicist/Emergency Planner
>mccartmj@state.mi.us
>
>Michigan Department of Environmental Quality
>Drinking Water and Radiological Protection Division
>Radiological Protection Section
>Nuclear Facilities Unit
>   phone:  517-335-9414
>     fax:  517-335-8706
>
>mailing address:
>     Michigan Department of Environmental Quality
>     Drinking Water and Radiological Protection Division
>     3423 North Martin Luther King Jr. Blvd
>     P.O. Box 30630
>     Lansing, MI 48909-8130
>
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