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Gonad Dose Guidelines?
RadSafers,
I have a researcher who is interested in administering small quantities of
radiolabled materials into pre-menopausal female volunteers. A cursory
estimate based on Fed Guide 11 and some conservative assumptions indicates
that the exposure to the gonads will be less than a mrem CEDE. However, a
possible concern is effects caused by the irradiation of an "egg" which can
later be fertilized.
What are the relevant guidelines and/or limits applicable to these
situations involving volunteers in clinical studies?
Appreciate your thoughts or references...
Scott Sorensen, RSO
ssorensen@saint-lukes.org
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