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FW: Loss of Taste after 100 mc Ablation Dose
> ----------
> From: Knapp, Steven J.
> Sent: Friday, March 19, 1999 9:54 AM
> To: 'dbeyea@nbnet.nb.ca'
> Subject: RE: Loss of Taste after 100 mc Ablation Dose
>
> I was interested enough to speak with a board certified nuclear medicine
> radiologist concerning the loss of taste after an I-131 therapy. An
> article in the Journal of Nuclear Medicine (J Nucl Med 1998; 39:1551-1554)
> discusses the intermediate and long-term side effects of high dose
> radioiodine treatment for thyroid carcinoma.
>
> The article states that to avoid damage to the salivary glands, patients
> are advised to increase their fluid intake, chew gum and suck on sour
> candies to promote discharge of radioiodine from the glands. The authors
> stated 76.8% of patients reported intermediate or long-term complaints of
> which 27% suffered from a transient, dose dependent loss of taste or
> smell. Long-term complaints consisted of reduced salivary gland
> production (radiation damage to the salivary glands) that resulted in dry
> mouth (42.9%), complete xerostomia (4.4%), recurrent conjunctivitis
> (22.7%) and increased frequency of influenza (13.8%). The authors
> discussed the use of the cisplatin antidote and radioprotector amifostin
> before radioiodine administration (expensive).
>
> A nuclear medicine radiologist stated that if a patient is orally
> administered liquid I-131, the high salty taste may persist during the
> therapy. I-131 administered in capsule form apparently does not have this
> side effect.
>
> Steve Knapp, Ph.D.
> Medical/Health Physicist
> steven.knapp@med.va.gov
>
> ----------
> From: Donald J. Beyea[SMTP:dbeyea@nbnet.nb.ca]
> Reply To: dbeyea@nbnet.nb.ca
> Sent: Thursday, March 18, 1999 9:21 AM
> To: Multiple recipients of list
> Subject: Loss of Taste after 100 mc Ablation Dose
>
> This is a multi-part message in MIME format.
>
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> Hi,
>
> Has anyone experienced patients complaining of a loss of TASTE after a 100
> mc I-131 ablation dose. If so is this a temporary or permanent feature?
> Thank You
>
>
> Donald Beyea
> Manager Nuclear Medicine
> Atlantic Health Science Corp.
> 506-648-6852
> dbeyea@nbnet.nb.ca
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> <html><head></head><BODY bgcolor=3D"#FFFFFF"><p><font size=3D4 =
> color=3D"#000000" face=3D"Times New Roman">Hi,<br><br>Has anyone =
> experienced patients complaining of a loss of TASTE after a 100 mc I-131 =
> ablation dose. If so is this a temporary or permanent =
> feature?<br>Thank You<br><br><br>Donald Beyea<br>Manager Nuclear =
> Medicine<br>Atlantic Health Science Corp.<br>506-648-6852<br><font =
> color=3D"#0000FF">dbeyea@nbnet.nb.ca<font color=3D"#000000"></p>
> </font></font></font></body></html>
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>
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