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University of Pittsburgh Graduate School of Public Health RADIATION SCIENCES SYMPOSIUM: CHEMOPREVENTION AND OXIDATIVE STRESS IN RADIATION EPIDEMIOLOGY *A symposium exploring the impacts of
chemoprevention and
oxidative stress on the reduction of health
risks from radiation exposures.*
Chemoprevention is the application of either
dietary or medicinal chemicals to lower the risk of disease. It is of particular
interest cancer and cardiovascular disease. The scientific evidence for
chemoprevention is clear yet complicated since there are many dietary
supplements, pharmaceuticals and ways to improve dietary balance that
potentially contribute to reduced incidence of cancers and other chronic
diseases. Public awareness of the benefits from chemoprevention is growing as
evidenced by lower
average consumption of saturated fats and
higher average consumption of fiber. Public health agencies everywhere are
promoting diets rich in vegetables, fruits
and fiber specifically to reduce the risks of cancer and cardiovascular disease.
Oxidative stress is a biochemical imbalance
between pro-oxidants and the antioxidant capacity of the biochemical system in
question. Oxidative damage to DNA, membranes and other critical biological
molecules is associated with a host of acute and chronic diseases including
cardiovascular disease and cancer. A major purpose of chemoprevention is to
maintain oxidative balance in cells and tissues in order to lower oxidative
damage to critical biochemical constituents of cells. This symposium explores
the impacts of chemoprevention and oxidative stress on cancer and other diseases
occurring from exposures to environmental or occupational agents. We are
inviting research presentations on:
o The basic cellular and molecular biology
of oxidative stress and chemoprevention;
o Current molecular and cellular hypotheses
on radiation-induced cancer and the role of oxidative stress in genomic
instability;
o The effects of chemopreventive lifestyles
on the risks of cancer and other chronic diseases;
o The possible effects of chemopreventive
lifestyles on radiation risks and radiation risk assessment.
Scientific Sessions:
THURSDAY, 21 OCT: Background in Oxidative Stress and Chemoprevention Cellular and Molecular Organismal Population Studies on Chemoprevention Dietary chemoprevention Medicinal chemoprevention Posters FRIDAY, 22 OCT: Radiation Epidemiology: Current Status Potential Impacts of Chemoprevention Workshop Session: Impact(s) of chemoprevention on Radiation Risk Assessment
LOCATION: University of Pittsburgh Pittsburgh, Pennsylvania October 21 - 22, 1999 Details will be sent with confirmation. Registration: A registration fee of $100 ($50 / student) is required. Please indicate you interest in ____ attending only ____ presentation ____ poster presentation and request addition materials by mail, fax or e-mail CORRESPONDENCE: Radiation Sciences Symposium University of Pittsburgh Environmental and Occupational Health 260 Kappa Drive Pittsburgh, PA 15238 Fax: 412- 624-1020 Phone: 412- 967-6514 E-Mail: mlcarion+@pitt.edu Checks payable to: University of Pittsburgh
Organizing Committee:
H. Gregg Claycamp, Ph.D., C.H.P. William L. Bigbee, Ph.D. Valerian E. Kagan, Ph.D., D.Sc. Evelyn O. Talbott, Dr.P.H. Niel Wald, M.D. Joseph Schwerha, M.D.
Abstract: (free form)
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