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Alpha dosimetry on lung epithelium
Dear radsafers,
I am searching for some alpha dosimetry algorithm in calculating the
lung epithelium dose from uniformly distributed alpha-emitted isotopes.
Particularly when the radionuclide is uniformly distributed on the inner
surface of the cylindrical bronchi and bronchioles with the mucus covering
the epithelium.
I find some formula in some articles in Radiation Protection
dosimetry(1991, pg 185-199) in terms of energy fluence rate and a
geometrical factor of (1+ (R/r)**2) but are just hard to figure out how it
come out!
Moreover I think that any alpha emission from a surface site towards a
target volume will be proportional to the solid angle subtended in that
target site due to the isotropic 4 pi geometry emission of that alpha
emission. Are there any articles or papers , textbooks on discussion with
that including continuous slow down approximation within the target tissue.
Thank you for any help in this topic.
Best regards
John Lam, Hong Kong
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