Re: Radon and Lung Cancer: What the studies really say.

[hflong@postoffice.pacbell.net]

Prof Field,

Selection of location could easily discredit those case control studies'

application to other areas. 



For example, radon in homes of cases and controls c100 Bq/m3 will be

found associated with LOWER lung cancer county mortality rates than

homes with USA average c50 Bq/m3 or less! That "U" curve is non-linear

and does not fit LNT and persists with hundreds of confounders

calculated separately.



Am CA Soc was wrong in applying your 1% outlier Iowa data to the

generalization, "Radon causes lung cancer", without specifying dose.

Most of the USA would appear to have LESS lung cancer if it had MORE

RADON!



Howard Long

  



epirad@mchsi.com wrote:

> 

> Fifteen out of the 18 major case-control studies reported an increased risk

> for radon exposure at 100 Bq/m3. This is also in agreement with the North

> American Residential pooling.  Further, unlike ecologic studies,

> misclassification in case-control studies generally bias the results torward

> no association as we have demonstrated previously.  As presented at a recent

> meeting of the American Statistical Society, the North American Residential

> Pooling study supports the LNT.

> 

>   http://www.aarst.org/news_pdf/2002_IowaU_Follow-up_Study.pdf

> >

> > On Wed, 18 Jun 2003 epirad@mchsi.com wrote:

> >

> > >  there have been innumerable case-control studies that support

> > > the LNT that have both external and internal validity.  I can provide details

> > > if you email me directly.

> >

> >       --There are case-control studies that seem to indicate agreement

> > with LNT and others that seem to indicate disagreement. The

> > statement normally made by those who present these studies is that they

> > are "consistent with" LNT. I don't remember statements that they "support"

> > LNT. Their statistics are too poor to make such claims.

> >

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