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Article: Radiation-induced heart disease.
I received this through another mailing list and
thought it would be of interest.
http://www.medscape.com/viewarticle/465851
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Radiation-Induced Heart Disease
Posted 02/11/2004
J. Willis Hurst, MD, MACP
I believe it is generally known that radiation to the
chest can cause pericarditis, coronary artery disease,
and myocardial disease. It is not generally
appreciated that radiation of the chest may cause
aortic valve disease.
Heidenreich and his colleagues studied 294
asymptomatic patients who had radiation of the
mediastinum for Hodgkin's disease.[1] They found that
a greater percentage of patients who received
radiation 20 years before evaluation had a higher
incidence of aortic regurgitation than those patients
who had received irradiation within 10 years.
The authors urge appropriate screening using
echocardiography to follow such patients.
--------------------------------------------------------------------------------
J. Willis Hurst, MD, MACP, Active Consultant to the
Division of Cardiology, Emory University School of
Medicine, Candler Professor and Chairman, Department
of Medicine Emeritus
Medscape Cardiology 8(1), 2004. © 2004 Medscape
[1] Heidenreich PA, Hancock SL, Lee BK, Mariscal CS,
Schnittger I. Asymptomatic cardiac disease following
mediastinal irradiation. J Am Coll Cardiol.
2003;42:743-749.
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