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An interesting question related to permanant prostate implant
>Here's what my friendly, neighborhood genetic counselor has told me (I
>have not been able to check any other references yet): any individual
>sperm are present and viable for about 3 months. Her sources say that a
>dose greater than 1 rad is enough to pose a substantial threat of DNA
>breakage. As we know, most of the DNA is non-coding. Damage to
>non-coding areas may never be expressed. However, there is a concern of
>chrmosome breakage, leading to crossovers, fragments, etc. This can be
>picked up by amnioscentesis. It is also possible for damage to occur
>causing an autosomal dominant mutation, which could either be lethal or
> still yield a viable fetus. It's also possible that a recessive
>mutation is formed that may or may not be expressed down the line. She
>recommended ultrasound at 20 weeks to look for the effect of any
>non-lethal autosomal dominant mutations. She also recommended
>amnioscentesis for chromosomal damage. No surprise, she felt that the
>patient (well, his partner) should talk to a knowlegeable genetic
>counselor in her area and go over their genetic history to see if there
>is also a specific risk they might be concerned about. I can get some
>references to that end if needed. Hope this helps. (The normal risk of
>genetic damage in a fetus is 3-5%.)
>
>Doug Pfeiffer
>
>--- "Haoran Jin, Ph.D." <hjin@EPIX.NET> wrote:
>> A doctor in my area asked me an interesting question: A gentleman
>> received
>> I-125 prostate seed implant 18 months ago. It's been 9 half life for
>> I-125
>> to decay since the implant. Now he made his partner pregnant. He
>> asked me
>> if it is safe to keep the baby? The sperms stay in the semminal
>> vessicle
>> for a short period of time (2 weeks at most?). I can estimate the
>> dose to
>> the sperm by calculating the dose to the semminal vessicle for 2
>> weeks. But
>> I don't know it is safe to have the baby. Is there anybody knowing
>> the
>> answer and like to share the answer with me? Please respond in
>> private
>> e-mail. Thanks
>>
>>
>> Haoran Jin, Ph.D.
>> hjin@epix.net
>>
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>
>===
>Douglas Pfeiffer, MS, DABR
>Presbyterian/St. Luke's Medical Center
>Medical Physics
>1719 E. 19th Ave.
>Denver, CO 80218
>(303)839-6548
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