Re: Alternative Iodine Administration Mechanism

[Shane Connor <shanec@gvtc.com>]

The following appears to pre-date the more recent study 
with dogs mentioned by Gene Carbaugh, but may still be 
of interest...

This excerpt below by Cresson H. Kearny is from his 1987 
updated version of Nuclear War Survival Skills (He wrote 
the original version while working as a research engineer 
at Oak Ridge National Laboratory.) Copy of this page here... http://www.ki4u.com/free_book/s73p924.htm 

"Research has been carried out in an effort to develop 
a thyroid protection procedure based on the ordinary iodine 
solutions which are used as disinfectants. Since iodine 
solutions such as tincture of iodine and povidone-iodine 
are dangerous poisons if taken orally, these experiments 
have utilized absorption through the skin after topical 
application on bare skin.

All reported experimental topical applications on human 
skin have given less thyroid protection than does proper 
oral administration of potassium iodide. Moreover, 
undesirable side effects of skin application can be serious. 
For these reasons researchers to date have not recommended a 
procedure for the use of ordinary iodine solutions for 
thyroid protection."

At 09:39 AM 11/2/99 -0800, you wrote:
>
>The recent thread about methods of blocking iodine brought 
>to mind a paper by Moody, et al., (1988), "The Effects of 
>Topical Povidone Iodine Solution on Serum Iodide Levels and 
>Thyroid Uptake of I-131 in Dogs," Health Physics 55:1(9-13). 
>They described what sounded like very good iodine protection 
>from painting 2-1/2% of the skin area with Betadine.  My check 
>of ICRP23 suggested that for an adult this would be about 450 
>square centimeters and for an infant about 75 sq cm.  I put 
>this in the back of my brain as an interesting alternative 
>to oral administration without the potential reactions which 
>might be associated with oral administration.  Has anyone 
>ever heard of any further work in this area?
>
>	Gene Carbaugh, CHP	
>	Internal Dosimetry
>	Pacific Northwest National Laboratory
>
>
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